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Arazlo® lotion: Uses, advantages, side effects, who can use it and how to use it

Table of Content:What is it? | What is it used for? | How does it work? | What makes it unique? | How does it help with acne? | Why is it less irritant? | Benefits | Side-effects | Precautions | Who is it for? | How to use Arazlo? | How to get it?

What is the Arazlo lotion?

Arazlo lotion® is a prescription medication used for the treatment of acne. Arazlo cream contains a combination of two active ingredients tazarotene and benzoyl peroxide and three moisturizing ingredients: sebacic acid, light mineral oil and sorbitol. This ingredient combination allows it to be extremely effective against acne while causing minimal skin irritation1.

What is Arazlo lotion used for?

The Arazlo cream is indicated for the treatment of psoriasis and acne vulgaris in patients 9 years of age and older. In addition to these uses, tazarotene, one of the active ingredients in Arazlo, is also being used for the treatment of wrinkles, hypo and hyperpigmentation and age spots (lentigines)2.

How does the Arazlo cream work?

The Arazlo lotion is applied topically on the affected areas and has a dual effect on the skin. On one hand, tazarotene (a newer retinoid) works by promoting skin cell turnover and reducing inflammation. On the other hand, benzoyl peroxide helps to kill the bacteria causing acne.

What makes the Arazlo lotion unique?

What makes the Arazlo lotion unique is its patented polymeric emulsion technology (which improves skin absorption and minimizes irritation) in addition to its list of active and moisturizing ingredients: tazarotene, benzoyl peroxide, sebacic acid, light mineral oil and sorbitol3.

What are the ingredients of the Arazlo lotion and how does it help with acne?

Tazarotene: Tazarotene is a synthetic acetylenic retinoid that undergoes hydrolysis in the body to its active form called tazarotenic acid. It works by normalizing the skin cell turnover process. It helps to prevent the clogging of pores and promotes the shedding of dead skin cells, which can contribute to the formation of acne. Tazarotene also has anti-inflammatory properties, reducing redness and swelling associated with acne4.

Benzoyl peroxide: Benzoyl peroxide is a topical medication used to treat acne. It works as a bactericidal agent, effectively killing acne-causing bacteria that contribute to acne. It also helps to decrease the production of sebum, which may clog pores and contribute to acne development. Benzoyl peroxide is not an antibiotic, which means it does not cause drug resistance, therefore it can be used long-term to treat acne without losing its effectiveness5.

By combining these two active ingredients, Arazlo addresses the different factors that contribute to acne development. Tazarotene helps normalize skin cell turnover and reduce inflammation, while benzoyl peroxide kills acne-causing bacteria and unclogs pores. Together, they work to improve existing acne lesions and prevent new ones from forming.

Why is Arazlo lotion less irritating than other acne products?

In addition to its acne-fighting ingredients tazarotene and benzoyl peroxide, the Arazlo lotion also contains emollient (diethyl sebacate) occlusive (light mineral oil) and humectant (sorbitol) ingredients.

What does this mean?

While all three ingredients contribute to moisturizing the skin, they may have different textures, absorption rates, and additional benefits.

Emollients mainly consist of lipids and ingredients that help fill gaps between skin cells, it helps to soften and hydrate the skin, providing a smooth and moisturized appearance6.

Occlusives are another type of moisturizer that is usually oil-based. They create a barrier on the skin, preventing water from escaping and keeping the skin hydrated7.

Humectants are moisturizers that contain substances that attract water. They help the outer layer of the skin absorb and retain moisture by drawing water from the deeper layers of the skin and the surrounding environment8.

In short, moisturizers can contain emollients, occlusives, and humectants. Emollients make the skin smooth and hydrated, occlusives create a barrier to lock in moisture, and humectants attract and retain water in the skin9.